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What are Germ Layers?

Michael Anissimov
Updated: May 21, 2024

Germ layers are the primary tissue layers in an animal, defined as groups of cells. Sponges have just one germ layer, cnidarians (jellyfish and relatives) have two, while all other animals have three. Animals with two germ layers are called diploblastic while those with three are called triploblastic. Most triploblasts have bilateral symmetry, while diploblasts have radial symmetry. Most sponges lack any symmetry.

The three germ layers are the ectoderm (outer layer), mesoderm (middle layer), and endoderm (inside layer). Cnidarians only have an ectoderm and an endoderm. It is thought that diploblastic animals evolved very early in the history of multicellular life, and may have actually been the first true multicellular organisms. Traditionally, scientists have thought that sponges evolved before cnidarians, but more recent genetic analysis has found that cnidarians are actually the oldest, and sponges are in fact a secondarily simplified phylum, probably evolving from diploblasts.

The division of the germ layers is especially evident during embryogenesis, when the embryo grows from a single fertilized egg into an organism ready to live on its own. Generally speaking, the ectoderm differentiates into the nervous system, epidermis, and the outer part of the integument system (hair, scales, nails, sweat glands, etc). The mesoderm differentiates into the wall of the gut, which cushions and organizes the internal organs. The endoderm differentiates into the lining cells of most of the internal organs, including the entire digestive system. Together the germ layers make up the organism.

The mesoderm is the great evolutionary innovation that allowed our triploblastic ancestors to effectively reproduce and open the door for complex, large animals. Triploblastic animals may be as much as 600 million years old. The key benefit of the mesoderm, unique to triploblasts, is the coelom, or body cavity, which has numerous useful functions. By cushioning the internal organs from external pressure, the organism is much less fragile. The coelom allows organs to grow independently of the body wall and keeps them organized. Also, the coelom allows a rudimentary hydrostatic skeleton, which consists of muscles pulling against the coelom wall. This is not a hard skeleton but a soft "skeleton" possessed by all triploblastic invertebrate life.

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Michael Anissimov
By Michael Anissimov
Michael Anissimov is a dedicated All The Science contributor and brings his expertise in paleontology, physics, biology, astronomy, chemistry, and futurism to his articles. An avid blogger, Michael is deeply passionate about stem cell research, regenerative medicine, and life extension therapies. His professional experience includes work with the Methuselah Foundation, Singularity Institute for Artificial Intelligence, and Lifeboat Foundation, further showcasing his commitment to scientific advancement.
Discussion Comments
By Esther11 — On Jun 01, 2011

Just think of all the man hours it has taken to learn as much as we now know about the process of evolution. Just think of all the wrong turns scientists have taken in the quest for answers to the many questions about evolution. Good thing so many scientists have passion for their work.

It sure took a long time for animals to evolve from germ layers. I don't think that there has been any noticeable evolutionary change in many, many years. I wonder if any changes are brewing under the surface!

By anon164780 — On Apr 02, 2011

what are the germ layers of a cheetah?

By averagejoe — On Aug 15, 2009

mjoyce: A germ layer is a group of cells in animals. I don't think they're poisonous. I don't think the "germ" in "germ layer" means a germ that you could infect another with.

By mjoyce — On Aug 15, 2009

Can a germ layer be used as a poison or a spray?

Michael Anissimov
Michael Anissimov
Michael Anissimov is a dedicated All The Science contributor and brings his expertise in paleontology, physics, biology...
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