We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What Is a Micropipette?

By Jay Leone
Updated: May 21, 2024

Micropipettes are a common type of laboratory equipment designed to transfer and measure very small amounts of liquid. They can be used to measure volumes as low as 0.003 ounce (0.1 milliliter). Standard micropipettes used in laboratory settings feature a few basic parts including an adjustment dial and a plunger button. Plungers on micropipettes are depressed with the thumb and when released, liquid can be drawn into a special plastic tip. There are several different sizes, types and styles of micropipette available.

The average micropipette consists of several components including a volume adjustment dial and a digital volume indicator. At the end of a shaft, these pipettes also feature an attachment point engineered to accommodate different types of disposable tips. Liquids are drawn into the disposable plastic tips fitted at the end of micropipette shafts instead of into the shafts themselves. The two main buttons found on most micropipettes are the plunger button and the tip ejector button. Pushing the ejector button will cause the pipette to immediately release the disposable tip at the end of the device.

Most micropipette plungers are designed to stop at two different positions. Depressing the plunger to the first stopping position and slowly releasing it will cause the pipette to draw the desired volume of liquid up into its disposable tip. Pressing a micropipette's plunger down further to the second stopping point releases the volume of fluid drawn into the device at the first stop. To draw an accurate measurement, pipette plungers should be pressed down to the first stop point before the pipette tip gets inserted into a sample.

Three of the more common micropipette sizes include P20, P200, and P1000. Each different size is designed to measure liquids within different volume ranges. The P20 micropipette can measure volumes within the range of 0.02 and 0.7 ounce (0.5 and 20 milliliters) while the P200 can measure volumes between 0.7 and 6.8 ounces (20 and 200 milliliters). P1000 micropipettes are some of the larger micropipettes available and are typically employed to measure liquids with a volume in the range of between 3.4 and 33.8 ounces (100 and 1,000 milliliters).

A micropipette's volume adjustment dial helps ensure accurate measurement. This component is used to adjust the volume of liquid entering the pipette's tip. As this dial is adjusted, the digital readout on the volume indicator will change to reflect the adjustment.

All The Science is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Link to Sources
Discussion Comments
All The Science, in your inbox

Our latest articles, guides, and more, delivered daily.

All The Science, in your inbox

Our latest articles, guides, and more, delivered daily.